Alchemist™ II screen making system

The Alchemist II automates the tedious and time-consuming task of producing crystallization matrices. With the best liquid handling accuracy available, the Alchemist II provides researchers an easy-to-use, low-maintenance solution for producing a broad range of coarse and fine screens for protein crystallography, carrying out the repetitive and time-consuming liquid dispense task based on a given recipe. The Alchemist II ensures that you will have reliable and repeatable results, enabling users to produce initial, optimization, additive, and detergent screens rapidly, reliably and without waste. Included with every Alchemist II, CrystalTrak™  is a relational database designed specifically for protein crystallography. CrystalTrak enables users to create crystallization screens simply and easily, allowing the setup of any type of gradient and then performing all the calculations and pipetting automatically into SBS, Linbro or Nextal plates.
		The Alchemist II SealTight BirdFeeder

The Alchemist II features:

• Industry-leading accuracy with the new Tapper™ technology enables dispensing down to 1 μl with a total CV of less than 2%
• Fast and easy to set up
• Holds up to 72 barcoded stock solutions in patent pending SealTight™ BirdFeeder containers
• No pumps, no tubing, no cross-contamination and no chemical waste
• Consistent, precise and accurate liquid dispensing in a volume range of 1 μl to 10 ml
• Non-contact, positive displacement pipetting
• One aspirate, multiple dispenses
• Stock usage tracking
• Multiple SealTight BirdFeeder sizes and syringe sizes
• Reliable storage of chemical stock in SealTight BirdFeeders
• Easy change of stock solutions
• Interchangeable plate nest adapters enable dispensing into SBS, Linbro and Nextal footprint plates
• Deep Well Block Stacker allows users to run multiple blocks in succession without having to swap blocks or plates between runs

The new SealTight BirdFeeders enable you to produce crystallization screens without waste and provide simple stock management and non-contact automated dispensing, while eliminating the maintenance and chemical waste associated with pumps, wash cycles and tubing.

With a single, dedicated syringe for every stock solution, you can be completely confident that there is absolutely no cross-contamination.

Truly modular—truly integrated

The Alchemist II can be used in a stand-alone configuration or as an integrated liquid handling system as part of the fully automated CrystalMation™ protein crystallization platform, guaranteeing that your system not only meets the needs of your lab today, but well into the future.

Electrical features

• 100-240 VAC 50/60 Hz 900 VA 

Physical parameters 

• Weight 800 lb (363 kg)
• Unit height 63.9" (162.3 cm), depth 30.6" ( 77.7 cm), width 49.5" (125.7 cm)

Alchemist II—Screen Making Made Easy