Protein crystallography
Sometimes referred to as macromolecular crystallography, this technique employs single crystal X-ray diffraction (SXRD) to unambiguously determine the 3D structure of large biological molecules. Pharmaceutical and biotechnology researchers need to understand how disease is controlled at the molecular level within proteins and related macromolecules so as to target specific entities based on this knowledge. A prerequisite for this approach is the ability to obtain high-resolution (3D) molecular structures of a protein, or other biologically active molecules, under investigation. Given the importance of this research, Rigaku has been at the forefront in the development of a wide range of instrumentation related to various aspects of protein crystallography.
Solutions
- X-ray diffraction systems
- Contract services
- Crystallization automation
- Cryogenics
- Crystal dehydration/recovery
- Detectors
- Goniometers
- Crystal mounting automation
- Optics
- SAXS
- Software
- Accessories