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"The recent upgrade of optics from Blues to VariMax HF has been a great success. Align­ment of optics is easier and sample exposure times across many projects has been cut in half, often with improve­ments in the final resolution of the data."

--Dr John Barker
Evotec (UK) Ltd

 
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VariMax optics shown with Picomotor actuators

580 Angstrom unit cell  
A 580 Å unit cell edge resolved with VariMax-HR optic on an R-AXIS IV++
(click for larger picture)


Superior spectral purity of VariMax compared to single bounce optics. VariMax beam profile is shown in solid lines; single bounce optic shown in dotted lines. Blue is Kα and red is Kβ
(click for larger picture)


Structure of the month

The structural charac­terization of the redundant thioredoxin system of Sulfolobus solfataricus

VariMax™ X-ray optics

Intense, uniform VariMax beam profile

VariMax, the latest generation of Confocal Max-Flux® (CMF) optics, is a landmark of innovative design and functionality. VariMax optics will increase output from most fine focus rotating anode generators but were specifically designed to achieve maximum performance when coupled with Rigaku microfocus X-ray generators. VariMax optical systems all feature a patented, continuously adjustable divergence slit assembly that enables users to adjust the X-ray beam divergence to allow for optimal spot separation for each crystal.

Different models of the VariMax optical system are available which have been designed and tested for specific applications and all VariMax optics provide superior performance compared to other X-ray optics. The long length of VariMax optics, compared to other multilayer optics, captures more of the X-ray beam from the microfocus generator resulting in higher flux. High flux, excellent spectral purity, uniform beam profile, and adjustable divergence make VariMax optics the ideal choice for single crystal diffraction experiments.

VariMax optic models

Model

Divergence range (mR)

Beam size at sample (mm)

Application

VariMax HR

 3.2 - 0

0.30

Protein crystallography with Cu radiation and crystals with long unit cells

VariMax HF

4.8 - 0

0.21

Protein crystallography with Cu radiation and small crystals

VariMax VHF

10 - 0

0.10

Protein crystallography with Cu radiation and very small crystals

VariMax Cr

3.2 - 0

0.45

Protein crystallography with Cr radiation for SAD phasing

VariMax Ag

2.7 - 0

0.18

Small molecule crystallography with Ag radiation for high Z electron density studies. Available in Kα and Kβ.

VariMax Co

3.2 - 0

0.39

Protein crystallography with Co radiation for SAD phasing

VariMax Mo

3.5 - 0

0.20

Small molecule crystallography with Mo radiation and small crystals