Protein crystallography
In medicine, biotechnology and pharmacology, pharmaceutical discovery is the process by which therapeutic agents are identified or designed. Even in the
recent past, most drugs have been discovered either by identifying the active ingredient in traditional remedies or by serendipitous discovery. A new
approach, using so-called "rational drug design," has been to understand how disease and infection are controlled at the molecular level within proteins and
other biological macromolecules so as to target specific entities based on this knowledge. A prerequisite for this approach is the ability to obtain high
resolution three dimensional (3D) molecular structures of the protein, or other biologically active molecules, under investigation. Given the importance of
this research, Rigaku has been at the forefront in the development of a wide range of instrumentation related to various aspects of protein crystallography.
Rigaku products range from automated crystallization and crystal imaging, through high-throughput crystal diffraction screening and high-resolution data
collection systems, to 3D structure refinement and imaging software. A pioneer and world leader in designing and manufacturing X-ray measurement tools
to solve single crystal X-ray diffraction challenges, Rigaku delivers cutting edge
solutions for protein crystallography applications.
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